What is your prescribed CRRT dose?
Could your CRRT dose intensity be doing harm?
To patients Ι To our environment Ι To budgets
Studies have shown no survival benefits with a dose higher than KDIGO recommendations.
Due to potential dialytrauma, prescribed doses above KDIGO may lead to...
- Prolonged oliguria1
- Delayed kidney recovery2
- Delayed ventilator weaning3
1- Mc Causland et al. Comparison of Urine Output among Patients Treated with More Intensive Versus Less Intensive RRT: Results from the Acute Renal Failure Trial Network Study. Clin J Am Soc Nephrol 2016, 11(8):1335-1342.
2- Wang et al. Renal replacement therapy intensity for acute kidney injury and recovery to dialysis independence: a systematic review and individual patient data meta-analysis. Nephrol Dial Transplant 2018, 33(6):1017-1024.
3-. Sharma et al. Intensity of Renal Replacement Therapy and Duration of Mechanical Ventilation: Secondary Analysis of the Acute Renal Failure Trial Network Study. Chest 2020, 158(4):1473-1481.
