Aquarius+ Software including dedicated RCA with low-volume sets

Dedicated Regional Citrate Anticoagulation (RCA) capability for low-volume patients

Regional citrate anticoagulation (RCA) is a safe and effective anticoagulation method for continuous renal replacement therapy (CRRT) in children, and could be more effective than systemic heparin anticoagulation.
Citrate has a lower incidence of bleeding complications because it has no systemic anticoagulation effects and does not induce thrombocytopeania.¹ Additional benefits of RCA may include: prolonged lifetime of the hemofilter circuit and reduced requirement for blood transfusions.^1,2

^{Swap between Heparin and/or Citrate during CVVH treatment without interruption.}

Consumables for the Aquarius™ System with RCA for low-volume patients
for Heparin and/or Citrate treatments

Aquamax^® filter

(Filter blood volume)

Aqualine S RCA

(Bloodline blood volume)

Total EC volume

(mL)

HF03

(32 mL)

Aqualine S RCA

(70 mL)

102

HF07⁺

(49 mL)

Aqualine S RCA

(70 mL)

119

1- Sik G, Demirbuga A, Annayev A, Citak A. Regional citrate versus systemic heparin anticoagulation for continuous renal replacement therapy in critically ill children. Int J Artif Organs.2020 Apr;43(4):234-241.

2- Zaoral, T, Hladik, M, Zapletalova, J, et al. Circuit lifetime with citrate versus heparin in pediatric continuous venovenous hemodialysis. Pediatr Crit Care Med 2016; 17(9): e399–e405.

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